- Search for Extraterrestrial Intelligence (SETI).
- Produce a forecast of the climate in the 21st century.
- Predict protein structure from protein sequence.
- Simulate particles traveling around the LHC particle accelerator
- Einstein@home (beta)
- Search for pulsars in data from LIGO and GEO 600. To join during the test phase you must go to Einstein@Physics2005
- Nano@home (not active)
- Design of nanometer-sized molecular machines.